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ADAPTIVE OPTICS VISION TESTING

The visual system adjusts to changes in the environment, as well as to changes within the observer, adapting continuously to maintain a match between visual coding and visual environment. The use of Adaptive Optics for correcting aberrations in the human eye opened the possibility of evaluating the effect of neural factors since the optical effects are compensated for.

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POLYCHROMATIC OPTICS

The visual world is polychromatic and the study of the impact of retinal image quality on vision should consider the aberrations in the visible light, as well as the effect of chromatic aberrations, and other optical phenomena. Modifying the ocular optics drastically changes the balance between monochromatic and chromatic aberrations.

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BIOPHOTONICS FOR MYOPIA RESEARCH

Biophotonics technologies can help to characterize myopic eyes in unprecedented details to gain novel insights, and to assess treatment effects objectively and comprehensively beyond conventional vision tests. In particular, unravelling the disruptions in the emmetropization process leading towards Myopia development can path the way to novel interventions to stop Myopia progression.

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AO BASED VISUAL SIMULATION

Adaptive optics based visual simulators with deformable mirrors, spatial light modulators or optotunable lenses are increasingly used to simulate vision through different complex multifocal lens designs. Their final utility in the clinic relies on their capability to predict visual performance after an ocular surgery.

PUBLICATIONS 
(peer reviewed journals)

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  • S Vedhakrishnan, A de Castro, M Vinas, S Aissati, S Marcos. Accommodation with simulated contact lenses in Myopes. Investigative Ophthalmology & Visual Science. June 2022, Vol.63(7). Q1

  • M Vinas-Pena, X Feng, G Li, S-H Yun. Investigating scleral crosslinking to stop myopia progression using optical coherence elastography. SPIE Photonics West 2022 proceedings. Conference: Optical Elastography and Tissue Biomechanics VIV. Symposium: PW22B SPIE BiOS. Paper No.: 11962-9.

  • S. Vedhakrishnan, A de Castro, M Vinas, S Aissati, S Marcos, "Accommodation through simulated multifocal optics," Biomedical Optics Express, 2022, 13, 6695-6710. Q1

  • M Vinas, X Feng, G Li, S Yun. In situ measurement of the stiffness increase in the posterior sclera after UV-riboflavin crosslinking by optical coherence elastography. Biomedical Optics Express, 2022: 13(10) Q1

  • S Aissati, C Benedí-García, M Vinas, A de Castro, S Marcos. Matching convolved images to optically blurred images on the retina. Journal of Vision. 2022;22(2):12. Q2

  • X Barcala, M Vinas, S Ruiz, F Hidalgo, D Nankivil, T Karkkainen, E Gambra, C Dorronsoro, S Marcos. Multifocal contact lens vision simulated with a clinical binocular simulator. Contact Lens and Anterior Eye, 2022; 101716. Q2

  • S Vedhakrishnan, M Vinas, C Benedi-Garcia, P Casado, S Marcos. Visual Performance with Multifocal lenses in Young Myopes and Presbyopes. PLoS ONE, 2022, 17(3): e0263659. Q1

  • M Vinas-Pena, A de Castro , C Dorronsoro, A Gonzalez-Ramos, S Redzovic, N Willet, N Garzon, S Marcos. Understanding In Vivo Chromatic Aberrations in Pseudophakic Eyes Using on Bench and Computational Approaches. Invited article in the Special Issue "Ocular Imaging for Eye Care". Photonics. 2022, 9(4), 226 . Q2

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  • RA Pérez, AI Gómez, F Gallazzi, B Santamaria, A de las Heras, MB Tomás, V González, M Delgado, M Viñas. SEDOPTICA-MOF: fomentando la igualdad de género. Reunión Nacional de Óptica 2021 proceedings. ISBN-13 978-84-09-37622-3. Simposio Miscelanea II.

  • S Aissati, M Vinas, C Benedi-Garcia, AM Gonzalez-Ramos, S Vedhakrishnan, S Marcos. Applications of Adaptive Optics Visual Simulators. Reunión Nacional de Óptica 2021 proceedings. ISBN-13 978-84-09-37622-3. OPTICA-SEDOPTIVA International Visual Sciences symposium.

  • CM Lago, A de Castro, L Sawides, S El Aissati, C Benedí-García, M Viñas, C Dorronsoro, S Marcos. Validation of EDOF IOL simulations in an Adaptive Optics visual simulator. Reunión Nacional de Óptica 2021 proceedings. ISBN-13 978-84-09-37622-3. OPTICA-SEDOPTIVA International Visual Sciences symposium.

  • F Gallazzi, JL Méndez González, J Nuño, D Puerto, S Aissati Aissati, X Barcala Gosende, C Benedí García, C Florian Baron, M García Lechuga, JL Luis García Pomar, R Gutiérrez Contreras, R Morea, P Pérez Merino, M Viñas-Peña.  Descubriendo la Luz: acercando la óptica a la sociedad. Reunión Nacional de Óptica 2021 proceedings. ISBN-13 978-84-09-37622-3. Simposio Miscelanea I.

  • S. Aissati, M Vinas, C. Benedi, S. Marcos. Convolved vs.Optically blurred images-What is the key reason for the observed differences? Investigative Ophthalmology & Visual Science June 2021, Vol.62, 1800. Q1

  • S Vedhakrishnan, M Vinas, S Aissati, S Marcos. Vision with Spatial Light Modulator simulating multifocal contact lenses in an Adaptive Optics system. Biomedical Optics Express, 2021 : 12, 2859-2872. Q1

  • C Benedi-Garcia, M Vinas, CM Lago, S Aissati, A de Castro, C Dorronsoro, S Marcos. Optical and visual quality of real intraocular lenses physically projected on the patient’s eye through a Rassow telescope. OSA Biomedical Optics Express, 2021; 12 (10). Q1

  • X. Barcala, M. Vinas, M. Romero, E. Gambra, J.L. Mendez-Gonzalez, S. Marcos, C. Dorronsoro. Multifocal Acceptance Score to Evaluate Vision: MAS-2EVTM. Nature Scientific Reports. 2021; 11 (1), 1-15). Q1

  • C. Benedi-Garcia, M. Vinas, C. Dorronsoro, S. Burns, Eli Peli, S. Marcos. Vision is protected against blue defocus. Nature Scientific Reports. 2021. volume 11, Article number: 352. Q1

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  • S. Marcos, S. Aissati, C. Benedi, C. Dorronsoro, E. Gambra, A. Radhakrishan, M. Vinas, M. Webster, L. Sawides. Visual Simulators: from understanding of vision mechanisms to applications in clinic. Journal of Vision 2019, Vol. 19, 15, 28. Q1

  • G. Muralidharan, J. Birkenfeld, M. Vinas, A. Curatolo, E. Martinez-Enriquez, A. De Castro, S. Marcos. Crystalline lens accommodation through multifocal corrections. Investigative Ophthalmology & Visual Science 2019, Vol.60, 1803. Q1

  • M. Vinas, et al. Optical and visual quality with physical and visually simulated presbyopic multifocal contact lenses. Investigative Ophthalmology & Visual Science 2019, Vol.60, 6468. Q1

  • X. Barcala, M. Vinas, E. Gambra, S. Marcos, C. Dorronsoro. Perceptual differences across binocular corrections for presbyopia. Investigative Ophthalmology & Visual Science 2019, Vol.60, 6469. Q1

  • S. Aissati, M. Vinas, C. Benedi-Garcia, C. Dorronsoro, S. Marcos. Testing the effect of ocular aberrations on perceived TCA. Investigative Ophthalmology & Visual Science 2019, Vol.60, 601. Q1

  • S. Vedhakrishnan, M. Vinas, S. Aissati, C. Benedi-Garcia, M. Romero, A. Gonzalez-Ramos, C. Dorronsoro, S. Marcos. Adaptive-optics vision simulation of multifocal lenses for myopia progression. Investigative Ophthalmology & Visual Science 2019, Vol.60, 605. Q1

  • A. Carmichael, M. Vinas, Ana Gonzalez-Ramos, C. Benedi-Garcia, C. Dorronsoro, S. Marcos, B. Vohnsen. Influence of the Stiles-Crawford effect of the first kind on visual acuity for decentered pupils. Investigative Ophthalmology & Visual Science 2019, Vol.60, 5943. Q1

  • S. Marcos, E. Martinez-Enriquez, M. Vinas, A. de Castro, C. Dorronsoro, S.P. Bang , G. Yoon , P. Artal. Simulating outcomes of cataract surgery: Important advances in Ophthalmology. Annual Review of Biomedical Engineering, 2020, Volume 23. Q1

  • M Vinas, S. Aissati, A.M. Gonzalez-Ramos, M. Romero, L. Sawides, V. Akondi, E. Gambra, C. Dorronsoro, T. Karkkainen, D. Nankivil, S. Marcos. Optical and visual quality with physical and visually simulated presbyopic MCLs. Translational Vision Science and Technology, 2020, 9 (10), 20-20. Q1

  • M Vinas, A.M. Gonzalez-Ramos, S. Aissati, N. Garzón, F. Poyales, C. Dorronsoro, S. Marcos. In vivo chromatic aberration with trifocal diffractive hydrophobic intraocular lenses. Journal of Refractive Surgery, 2020;36(12):804-10. Q1

  • S. Aissati, M. Vinas, C. Benedi-Garcia, C. Dorronsoro, S.Marcos.  Testing the effect of ocular aberrations in the perceived Transverse Chromatic Aberration. OSA Biomedical Optics Express, 2020; 11, 4052-68. Q1

  • S. Marcos, M. Romero, C. Benedí-García, A. M. González,  M. Vinas, N. Alejandre, I. Jiménez-Alfaro, Interaction of monochromatic and chromatic aberrations in pseudophakic patients. Journal of Refractive Surgery. 2020; 36(4):230-238. Q1

  • S. Marcos, S, Benedí‐García, C, Aissati, S, Gonzalez‐Ramos, AM, Lago, CM, Radhkrishnan, A, Romero, M, Vedhakrishnan, S, Sawides, L & Vinas, M. VioBio lab adaptive optics: technology and applications by women vision scientists. Invited Article on Adaptive Optics in The Ida Mann 2020 Special Issue. Ophthalmic Physiol Opt, 2020; 40: 75– 87. Q1 

 

  • P. Perez-Merino, D. Siedlecki, L. Remon, M. Vinas, J. Alio, J. Rozema. Personalized Optical Designs and Manipulating Optics: Applications on the Anterior Segment of the Eye. Editorial. Journal of Ophthalmology. Article ID 9586062. December 2019. Q2

  • M. Vinas, S. Aissati, M. Romero, C. Benedi-Garcia, N. Garzon, F. Poyales, C. Dorronsoro, S. Marcos. Pre-operative simulation of post-operative multifocal vision. OSA Biomedical Optics Express, 2019;10(11): 5801-17 Q1

  • C. Dorronsoro, X. Barcala, E. Gambra, V. Akondi, L. Sawides, Y. Marrakchi, V. Rodriguez-lopez, C. Benedi-garcia, M. Vinas, E. Lage, S. Marcos. Tunable lenses: dynamic characterization and fine-tuned control for high-speed applications. OSA Optics Express, 2019 ; 27 (3) : 2085-2100. Q1

  • M. Vinas, C. Benedi-Garcia, S. Aissati, D. Pascual, V. Akondi, C. Dorronsoro, S. Marcos. Visual simulators replicate vision with multifocal lenses.  Nature Scientific Reports. 2019 ; 9 (1): 1539. Q1

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  • S. Marcos, M. Vinas, A. Gonzalez-Ramos, S. Aissati, C. Dorronsoro, N. Garzon, F. Poyales. In vivo chromatic aberration in patients implanted with hydrophilic and hydrophobic monofocal and FineVision trifocal IOLs. ESCRS 2018, Viena (Austria)

  • X. Barcala, M. Romero, M. Vinas, JL Mendez-Gonzalez, E. Gambra, C. Dorronsoro, S. Marcos. Repeatability of the multifocal acceptance score (MAS). ESCRS 2018, Viena (Austria)

  • M. Vinas, et al. Comparison of multifocal visual simulations in patients before and after implantation of diffractive trifocal lenses. Investigative Ophthalmology & Visual Science July 2018, Vol.59, 252. Q1

  • S. Marcos; C. Benedi; M. Vinas; C. Dorronsoro; S. A Burns; E. Peli. Visual benefit of correcting HOAs in blue or green light: an optical effect? Investigative Ophthalmology & Visual Science July 2018,Vol.59,654Q1

  • S. Marcos, M. Vinas, C. Dorronsoro, L. Sawides, E. Gambra, C. Benedi, S. Aissati. Adaptive-Optics based visual simulators: from on-bench to wearable devices (invited talk). OSA Imaging and Applied Optics Congress. Meeting Adaptive Optics: Methods, Analysis and Applications 2018, Orlando (USA)

  • S. Aissati, M. Vinas, M. Romero, C. Benedi, V. Akondi, C. Dorronsoro, S. Marcos. Visual simulation of multifocal lenses in patients before & after implantation of diffractive trifocal lenses. AOIM XI 2018, Murcia (Spain).

  • C. Benedi-Garcia, M. Vinas, C. Dorronsoro, E. Peli, S. Burns, S. Marcos. Impact of the interactions between mono- and chromatic aberrations on visual function. AOIM XI 2018, Murcia (Spain).

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  • M. Vinas, et al. In vivo measurement of longitudinal chromatic aberration with multifocal diffractive intraocular lenses. Investigative Ophthalmology & Visual Science 2017, Vol.58, Issue 8, 337. Q1

  • V. Akondi, E. Gambra, M. Vinas, S. Aissati, C. Dorronsoro, D. Pascual, S. Marcos. Simulating multifocal intraocular lenses with a SLM and a tunable lens. Investigative Ophthalmology & Visual Science 2017, Vol.58 (8), 1272. Q1

  • S. Marcos, M. Vinas, C. Benedi, S. Aissati, V. Akondi, X. Barcala, E. Gambra. Visual simulations of real multifocal lenses in a multi-channel Adaptive Optics system. Investigative Ophthalmology & Visual Science 2017, Vol.58, Issue 8, 1248. Q1

  • M. Vinas, A.M. Gonzalez-Ramos, C. Dorronsoro, V. Akondi, N. Garzon, F. Poyales, S. Marcos. In vivo measurement of LCA in patients implanted with trifocal diffractive intraocular lenses. Journal of Refractive Surgery. 2017; 33 (11): 736-742. Q1

  • M. Vinas, C. Dorronsoro, A. Radhakrishnan, C. Benedi-Garcia, E.A. LaVilla, J. Schwiegerling, S. Marcos. Comparison of vision through surface modulated and spatial light modulated multifocal optics. OSA Biomedical Optics Express, 2017 ; 8(4) : 2055-2068. Q1

  • M. Vinas, C. Dorronsoro, V. Gonzalez, D. Cortes, A. Radhakrishnan, S. Marcos. Testing vision with angular and radial multifocal phase patterns using adaptive optics.  Vision Research, special issue, 2017; 132: 85-96. Q1

  • M. Vinas, C. Dorronsoro, N. Garzón, F. Poyales, S. Marcos. In vivo subjective and objective LCA in patients bilaterally implanted with same design hydrophobic and hydrophilic IOLs. Journal of Cataract and Refractive Surgery, 2015 ; 41 (10). Q1

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  • V. Akondi, E. Gambra, M. Vinas, D. Pascual, S. Aissati, S. Marcos. "Temporal multiplexing and simulation of MIOLs“. Frontiers in Optics 2016 OSA Technical Digest (Optical Society of America, 2016), paper FW2A.3

  • M. Vinas, et al. Testing vision with physical and simulated multifocal corrections in an adaptive optics visual simulator. Investigative Ophthalmology & Visual Science 2016, Vol.57, Issue 12, 3128. Q1

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  • M. Vinas, et al. Testing vision with radial and angularly segmented multifocal patterns using adaptive optics. Investigative Ophthalmology & Visual Science 2015, Vol.56, Issue 7, 1358. Q1

  • E. LaVilla, M. Vinas, S. Marcos, and J. Schwiegerling, "Freeform Design of Multifocal Zone Plates ," in Imaging and Applied Optics 2015, OSA Technical Digest (online) (Optical Society of America, 2015), paper FW3B.3.

  • M. Vinas, C. Dorronsoro, D. Cortes, D. Pascual, S. Marcos. LCA of the human eye in the visible and near infrared from wavefront sensing, double-pass & psychophysics. OSA Biomedical Optics Express,2015;23(4)Q1

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  • M. Vinas, et al. Optical performance with multi-zone multifocal designs with natural and corrected ocular aberrations. Frontiers in Optics 2014 OSA Technical Digest (Optical Society of America, 2014), JW3A.37

  • M. Vinas, et al. Longitudinal Chromatic Aberration of the human eye in the visible and near infrared from Hartmann-Shack wavefront sensing, double-pass and psychophysics. Investigative Ophthalmology & Visual Science 2014, Vol.55, Issue 13, 5974. Q1

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  • M. Vinas, et al. Visual performance under natural, corrected and Adaptive Optics induced astigmatism: meridional and adaptational effects. Investigative Ophthalmology & Visual Science  2013, Vol.54(15)1281. Q1

  • M. Vinas, P. de Gracia, C. Dorronsoro, L. Sawides, G. Marin, M. Hernández, S. Marcos. Astigmatism impact on visual performance: meridional & adaptational effects. Optometry and Vision Science,  2013 ; 90 (12); Q1

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  • L. Sawides, C. Dorronsoro, P. de Gracia, M. Vinas, M. Webster, A. Haun, E. Peli, S. Marcos. Natural Adaptation to the Orientation of HOAs. Investigative Ophthalmology & Visual Science 2012, Vol.53, Issue 14, 3659. Q1

  • M. Vinas, et al. Longitudinal Changes in Perceptual Judgment Of Astigmatic Blur. Investigative Ophthalmology & Visual Science 2012, Issue 14, Vol.53, 3656. Q1

  • M. Vinas, L. Sawides, P. de Gracia, S. Marcos. Perceptual adaptation to the correction of natural astigmatism. PLoS ONE 7(9): e46361; September 2012; DOI:10.1371/journal.pone.0046361. Q1

  • L. Sawides, C. Dorronsoro, P. de Gracia, M. Vinas, M. Webster, S. Marcos. Dependence of subjective image focus on the magnitude and pattern of HOAs. Journal of Vision, 2012 12(8): 4. Q1

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  • M.Vinas, et al. AO as a tool to study changes in the perceived neutral point after correction of astigmatism. 8th Workshop on AO for Industry and Medicine (Murcia, Spain). AOIM Droplets in Murcia, 2011

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  • C. Sanchez ,M. Vinas , M. Perez, E. Gomez, Y. Diaz, M. Sillero. Optical filters influence on pupil size according to their material and spectral characteristics. Acta Ophthalmologica, 87: 0, 2009. DOI: 10.1111/j.1755-3768.2009.357.x. Q1

  • C. Sanchez, C. Bonin, R. García, M. Vinas, E. Chamorro, E. Gómez. Variation of mesopic and photopic spatial resolution in drivers older than 65 years old. Proceedings of the International Symposium on Automotive Lighting (ISAL). 2009

  • M. Sanchez, C. Wasfi, C. Bonnin, M. Vinas, A. Forlan, C. Molina, E. Chamorro. Evaluation and inter-observer analysis of retinography existing clinical classification system to categorize moderate retinopathies. Acta Ophthalmologica, Volume 87, Issue s244, 2009. Q1

  • M. Vinas, et al. Optical filter quality effect on pupil size in night driving. Proceedings of the International Symposium on Automotive Lighting (ISAL) 2009

  • C. Sanchez , M. Vinas, M. Perez, E. Gomez, Y. Diaz, M. Sillero. Optical filters influence on pupil size according to their material & spectral characteristics. Acta Ophthalmol, 87: 0, 2009. DOI: 10.1111/j.1755-3768.2009.357.x. Q1

  • E. Gómez, C. Sanchez, M. Vinas, C. Bonnin, B. Gallego. Lighting influence in the perception of the contrast of objects in movement by using frequency doubling technology (FDT) Proceedings of the International Symposium on Automotive Lighting (ISAL). 2009

  • MJ. Perez, C. Sanchez, M. Vinas, C. Bonnin, A. Forlan, M. San Miguel, G. Ramírez. Analysis of Intra-observer's Repeatability in Retinopathy's Classification of Patients With Clear And Yellow Iol's Implantation. Investigative Ophthalmology & Visual Science 2009, Issue 23, Vol.50, 745. Q1

 

  • C. Sanchez, Y. Diaz, M. Vinas, E. Rodrigo, C. Bonnin, M. Sillero. Variability of pupil behaviour due to different retinal’s illumination levels. Acta Ophthalmologica, 86 : 0 (2008). DOI: 10.1111/j.1755-3768.2008.444.x. Q1

  • C. Sanchez, M. Vinas, Y. Diaz, C. Torets. Effect of the interposition of optical filters with different visible light transmittances in mesopic & scotopic condition pupil size. Acta Ophthalmol, 86: 0 (2008). DOI: 10.1111/j.1755-3768.2008.452.x. Q1

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